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This assistance is not really meant to define registration and/or submitting prerequisites or modify pharmacopoeial specifications. This steering doesn't impact the power on the liable regulatory company to ascertain precise registration/submitting demands pertaining to APIs in the context of promoting/manufacturing authorizations or drug apps. All

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Please Observe: Wiley-Blackwell aren't chargeable for the articles or features of any supporting resources equipped with the authors. Any queries (apart from missing materials) ought to be directed to the corresponding writer for your write-up., 2003). The point that COMT exercise is improved even in α2BKO mice demonstrates this catabolic pathway

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